Journal
CHEMICAL SCIENCE
Volume 4, Issue 5, Pages 2100-2104Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3sc50410g
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Funding
- NIGMS CMLD program [P50GM069721]
- American Cancer Society
- NSERC
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Highly enantioselective vicinal iodoamination of olefins is accomplished through the iodocyclization of alkenyl trichloroacetimidates catalysed by a new chiral Schiff-base urea derivative. The resulting products are converted readily to a variety of polyfunctional amine-containing chiral building blocks.
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