4.8 Article

Supramolecular control over Diels-Alder reactivity by encapsulation and competitive displacement

Journal

CHEMICAL SCIENCE
Volume 3, Issue 3, Pages 785-788

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1sc00847a

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Funding

  1. European Research Council
  2. Netherlands Organization for Scientific Research (NWO)

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A water-soluble M4L6 coordination cage was used as a supramolecular protecting group in the Diels-Alder reaction between furan and maleimide. Encapsulation of furan in the cage prevents the Diels-Alder reaction, while subsequent addition of a competing guest will initiate the reaction.

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