4.8 Article

Catalytic enantioselective electrocyclic cascades

Journal

CHEMICAL SCIENCE
Volume 3, Issue 2, Pages 537-540

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c1sc00697e

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Funding

  1. Royal Society
  2. EPSRC
  3. Pfizer
  4. GSK
  5. European Research Council under the European Community [259056]

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A catalytic enantioselective electrocyclic cascade leads to the construction of topologically complex systems comprising multiple rings with up to three stereocentres. This phase-transfer catalysed process offers a new strategy for the rapid and enantioselective generation of complex products bearing all-carbon quaternary stereogenic centres.

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