Journal
CHEMICAL SCIENCE
Volume 3, Issue 2, Pages 327-334Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1sc00544h
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Funding
- National Natural Science Foundation of China [20732003, 21021001]
- Major Basic Research Program of China (973 Program) [2010CB833300]
- Sichuan University
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The enantioselective synthesis of 3-functionalized oxindole derivatives has experienced an explosive development. This minireview introduces the recent application of rare earth (RE) metal complex catalysts in the synthesis of targeted frameworks. The direct addition reactions of 3-substituted oxindoles or isatins are described, together with a discussion of the catalytic mechanism and related transformations to pharmaceuticals.
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