4.8 Article

Highly selective additions of hydride and organolithium nucleophiles to helical carbenium ions

Journal

CHEMICAL SCIENCE
Volume 2, Issue 3, Pages 425-428

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0sc00525h

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Funding

  1. Swiss National Science Foundation, the State Secretariat for Education and Science

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Unsymmetrical cationic [4] helicenes react with hydride or organolithium reagents and the two diastereotopic faces can be discriminated with high efficiency (dr up to and higher than 49 : 1)

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