4.8 Article

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

Journal

CHEMICAL SCIENCE
Volume 2, Issue 2, Pages 287-290

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0sc00524j

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Funding

  1. Novartis International AG

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A continuous-flow palladium-catalyzed amination reaction was made possible through efficient handling of solids via acoustic irradiation. Various diarylamines were obtained with reaction times ranging from 20 s to 10 min.

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