Journal
JACC-CARDIOVASCULAR IMAGING
Volume 5, Issue 2, Pages 214-226Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jcmg.2011.11.009
Keywords
cardiac metabolism; imaging; tracers
Funding
- NHLBI NIH HHS [R01 HL061483, R01 HL073162-05, R01 HL073162, R01 HL061483-10, T32 HL007591-15, T32 HL007591] Funding Source: Medline
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Tracer techniques are powerful methods for assessing rates of biological processes in vivo. A case in point is intermediary metabolism of energy providing substrates, a central feature of every living cell. In the heart, the tight coupling between metabolism and contractile function offers an opportunity for the simultaneous assessment of cardiac performance at different levels in vivo: coronary flow, myocardial perfusion, oxygen delivery, metabolism, and contraction. Noninvasive imaging techniques used to identify the metabolic footprints of either normal or perturbed cardiac function are discussed. (J Am Coll Cardiol Img 2012;5:214-26) (C) 2012 by the American College of Cardiology Foundation
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