One Pot Synthesis of New Gold Nanoparticles Dispersed Poly(2-aminophenyl boronic acid) Composites for Fabricating an Affinity Based Electrochemical Detection of Glucose

In this investigation, a facile one step synthesis was utilized to prepare gold nanoparticles (Au NPs) dispersed poly(2-aminophenyl boronic acid) (PAPBA) nanocomposite (PAPBA/Au-NC). PAPBA/Au-NC was characterized by field effect scanning electron microscopy, Fourier transform infrared spectroscopy and thermogravimetric analysis. The synergistic properties of the boronic groups, conducting polyaniline matrix and Au NPs in the new PAPBA/Au-NC were effectively utilized for the fabrication of a high sensitive non-enzymatic glucose sensor electrode. The sensor electrode was characterized by cyclic voltammetry and electrochemical impedance spectroscopy. We demonstrated that the new non-enzymatic sensor electrode exhibited good electrocatalytic activity for the oxidation of glucose. The Au NPs, PANI and boronic groups synergistically influence electrochemical detection of glucose. PAPBA/Au-NC exhibited excellent selectivity for glucose, good electron transduction to the electrode and high electrochemical sensitivity. The greater progress achieved in this investigation will pave the way for the potential development of a practical non-enzymatic glucose sensor.