Journal
VIRUSES-BASEL
Volume 6, Issue 9, Pages 3514-3534Publisher
MDPI
DOI: 10.3390/v6093514
Keywords
mosquito; arbovirus; gene regulation; microRNA
Categories
Funding
- Australian Research Council [DP110102112]
- National Health and Medical Research Council [APP1027110]
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The role of microRNAs (miRNAs) as small non-coding RNAs in regulation of gene expression has been recognized. They appear to be involved in regulation of a wide range of cellular pathways that affect several biological processes such as development, the immune system, survival, metabolism and host-pathogen interactions. Arthropod-borne viruses impose great economic and health risks around the world. Recent advances in miRNA biology have shed some light on the role of these small RNAs in vector-virus interactions. In this review, I will reflect on our current knowledge on the role of miRNAs in arbovirus-vector interactions and the potential avenues for their utilization in limiting virus replication and/or transmission.
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