Journal
VIRUSES-BASEL
Volume 3, Issue 4, Pages 293-311Publisher
MDPI
DOI: 10.3390/v3040293
Keywords
HIV; actin cytoskeleton; entry; Nef; cofilin
Categories
Funding
- Deutsche Forschungsgemeinschaft [SFB 638, GRK1188]
Ask authors/readers for more resources
The host cell cytoskeleton plays a key role in the life cycle of viral pathogens whose propagation depends on mandatory intracellular steps. Accordingly, also the human immunodeficiency virus type 1 (HIV-1) has evolved strategies to exploit and modulate in particular the actin cytoskeleton for its purposes. This review will recapitulate recent findings on how HIV-1 hijacks the cytoskeleton to facilitate entry into, transport within and egress from host cells as well as to commandeer communication of infected with uninfected bystander cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available