Two New Stilbenoids from Cajanus cajan

Z. Naturforsch. 2012, 67b, 1314-1318 / DOI: 10.5560/ZNB.2012-0184 Received July 5, 2012 Two new stilbenoids cajanotone and cajanamide A (1-2), together with another six known ones (3-8) and four known dihydroflavones (9-12), have been isolated from the leaves of Cajanus cajan. Their structures were elucidated based on spectroscopic studies. A possible pathway to the new compounds 1 and 2 has been proposed. In vitro cytotoxicities of selected compounds against cancer cell lines HepG2, MCF-7 and A549 have been evaluated. Compounds 7 and 8 show strong cytotoxity against all the tested cell lines (with IC50 values in the range of 3.5-6.0 mu m), and compounds 1 and 3 showed strong to moderate activity against the three cell lines.