4.0 Article

Terpenoids from Clerodendrum formicarum Gurke (Lamiaceae) of Cameroon

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/znb-2010-0414

Keywords

Formidiol; abeo-Abietane; Leaves; Clerodendrum formicarum; Lamiaceae; Characterization; Spectroscopy

Funding

  1. Higher Education Commission, Islamabad (Pakistan)
  2. Indigenous Ph. D. 5000 Fellowship Program

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=The ethanolic extract of the leaves of Clerodendrum formicarum, a Lameacious plant of Cameroon, afforded a new abeo-abietane diterpenoid named formidiol (1) together with some known di- and triterpenoids. They include 12, 16-epoxy-11, 14-dihydroxy-6-methoxy-17(15 -> 16)-abeo-abieta-5,8,11,13,15-pentanene-3,7-dione (2), trans-phytol, friedelin and friedlan-3 beta-ol. Structures of all the isolated constituents have been characterized with the aid of ID NMR spectroscopy while the structure of a new metabolite was elucidated via 2D NMR spectroscopic techniques.

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