Journal
YONSEI MEDICAL JOURNAL
Volume 52, Issue 5, Pages 851-855Publisher
YONSEI UNIV COLLEGE MEDICINE
DOI: 10.3349/ymj.2011.52.5.851
Keywords
Regulatory B cell; CD5; CD19; IL-10; CD5(+) B
Categories
Funding
- Korean Ministry of Education, Science and Technology (Chungbuk BIT Research-Oriented University Consortium)
- Ministry for Health, Welfare & Family Affairs, Republic of Korea [A084847]
- Korea Health Promotion Institute [A084847] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
IL-10 production by CD19(+)CD5(+) B cells was investigated, by determining the expression levels of CD19, a classical B cell marker. Peripheral mononuclear cells were stained with fluorescence-conjugated anti-CD5, anti-CD19, anti-IL-10, and Annexin V. Interestingly, IL-10-producing B cells were found to be localised within the CD19(low)CD5(+) B cell subset. Apoptotic changes were also observed mainly in CD19(low) cells among B cells. Thus, CD5(+) B cells should be classified as CD19(high) and CD19(10w) cells, and the immunological significance of CD19 for the IL-10 production by CD5(+) B cells requires further studies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available