Journal
XENOTRANSPLANTATION
Volume 16, Issue 6, Pages 496-501Publisher
WILEY
DOI: 10.1111/j.1399-3089.2009.00554.x
Keywords
chemistry; coagulation; hematology; reference values; rhesus monkey
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Funding
- National Basic Research Program of China [2009CB522401]
- National Program for High Technology Research and Development of China [2006AA02A117]
- National Natural Science Foundation of China [30772037]
- China Postdoctoral Science Foundation [20080430195]
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Background: Rhesus monkey models are valuable to the studies of human biology. Reference values for clinical chemistry and hematology parameters of rhesus monkeys are required for proper data interpretation. Methods: Whole blood was collected from 36 healthy Chinese rhesus monkeys (Macaca mulatta) of either sex, 3 to 5 yr old. Routine chemistry and hematology parameters, and some special coagulation parameters including thromboelastograph and activities of coagulation factors were tested. Results and conclusion: We presented here the baseline values of clinical chemistry and hematology parameters in normal Chinese rhesus monkeys. These data may provide valuable information for veterinarians and investigators using rhesus monkeys in experimental studies.
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