The use of prefabrication technique in microvascular reconstructive surgery

Aim of the study: The aim,of the study Was to develop standards for the pre-fabrication of free microvascular flaps in an animal model, followed by their application in clinical practice,and quantitative/qualitative microscopic assessment of the extent of development of,a new microvascular: network. Material and methods: The study was carried out in 10 experimental pigs. As the first stage, a total Of 20 prefabricated flaps were created using polytetrafluoroethylene (PTFE) as a-Support material, placed horizontally over an isolated and:distally closed vascular,pedicle based on superficial abdominal vessels. After completing the animal model study, one patient was selected for the grafting of the prefabricated free flap. Results: All 20 free flaps prefabricated in the animal model were analyzed microscopically, exhibiting connective tissue rich in fibroblasts and small blood yes-sets in the porous areas across the entire thickness of the,PTEE element. Conclusions: Flap prefabrication is a new and fast developing reconstruction technique. The usefulness of;prefabrication techniques and their status in reconstructive surgery still needs to be investigated experimentally and clinically. The Method based on prefabricated free flaps is the first step towards anatomical;bioengineering that will make it possible to replace missing organs, with their anatomically perfect equivalents.