Journal
WOUND REPAIR AND REGENERATION
Volume 21, Issue 4, Pages 498-502Publisher
WILEY
DOI: 10.1111/wrr.12052
Keywords
-
Funding
- Fonds pour la Recherche en Sante du Quebec (FRSQ)
- FRSQ
- Canadian Institutes of Health Research
Ask authors/readers for more resources
Negative-pressure wound therapy (NPWT) has significantly improved healing rates and patient comfort since its inception. However, a considerable number of questions have been raised regarding its mechanisms of action. Many health care workers and researchers have attempted to clarify the role of NPWT in wound healing. The purpose of this perspective article is to assemble some of the concepts that have been put forward in order to propose an integrated view of the mechanisms involved in NPWT. Particular emphasis will be placed on mechanically induced tissue deformations and their involvement in some of the key processes of wound healing, including nutrient and oxygen transport, blood vessel formation, and cellular proliferation and differentiation, mainly of myofibroblasts.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available