Journal
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
Volume 30, Issue 3, Pages 1135-1139Publisher
SPRINGER
DOI: 10.1007/s11274-013-1531-x
Keywords
Marine gliding bacterium; Rapidithrix thailandica; Amino phenyl pyrrolidone derivative; Antibacterial activities; Vancomycin-resistant Enterococcus faecalis (VRE)
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Funding
- Prince of Songkla University
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A recently described marine gliding bacterium Rapidithrix thailandica strain TISTR 1741 was isolated from biofilm specimen collected from the Andaman Sea in Thailand. Four liters fermentation broth of R. thailandica TISTR 1741 cultivated in VY/2 medium were extracted with methanol to yield a novel amino phenyl pyrrolidone derivative compound (1) with antibacterial activities. The chemical structure and physico-chemical properties of 1 were investigated by spectrometry techniques. Compound 1 exhibited selective inhibition against vancomycin-resistant Enterococcus faecalis (VRE) with the MIC of 5.97 mM.
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