Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 20, Issue 40, Pages 14717-14725Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v20.i40.14717
Keywords
Pancreatic cancer; Diagnosis; Treatment; Signaling pathways; Nanomedicine; Biomarkers
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Funding
- National Institutes of Health (NIH) R01 [5R01CA167535-02]
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With the incidence reports of pancreatic cancer increasing every year, research over the last several decades has been focused on the means to achieve early diagnosis in patients that are at a high risk of developing the malignancy. This review covers current strategies for managing pancreatic cancer and further discusses efforts in understanding the role of early onset symptoms leading to tumor progression. Recent investigations in this discussion include type 3c diabetes, selected biomarkers and pathways related to pancreatic intraepithelial neoplasia lesions, drug resistance, and advances in nanomedicine which may provide significant solutions for improving early detection and treatments in future medicine. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.
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