4.6 Review

Management of small hepatocellular carcinoma in cirrhosis: Focus on portal hypertension

Journal

WORLD JOURNAL OF GASTROENTEROLOGY
Volume 19, Issue 8, Pages 1193-1199

Publisher

BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v19.i8.1193

Keywords

Portal hypertension; Hepatic venous pressure gradient; Clinically significant portal hypertension; Liver stiffness; Liver cancer; Hepatocellular carcinoma; Resection; Radiofrequency ablation; Percutaneous ethanol injection

Ask authors/readers for more resources

The incidence of hepatocellular carcinoma (HCC) is rising worldwide being currently the fifth most common cancer and third cause of cancer-related mortality. Early detection of HCC through surveillance programs have enabled the identification of small nodules with higher frequency, and nowadays account for 10%-15% of patients diagnosed in the West and almost 30% in Japan. Patients with small HCC can be candidates for potential curative treatments: liver transplantation, surgical resection and percutaneous ablation, depending on the presence of portal hypertension and co-morbidities. This review will analyze recent advancements in the clinical management of these individuals, focusing on issues related to the role of portal hypertension, the debate between resection and ablative therapies and the future impact of molecular technologies. (C) 2013 Baishideng. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available