Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 17, Issue 42, Pages 4647-4653Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v17.i42.4647
Keywords
Non-steroidal anti-inflammatory drugs; Small intestinal injury; Prevention; Treatment
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Non-steroidal anti-inflammatory drug (NSAID)-induced small bowel injury is a topic that deserves attention since the advent of capsule endoscopy and balloon enteroscopy. NSAID enteropathy is common and is mostly asymptomatic. However, massive bleeding, stricture, or perforation may occur. The pathogenesis of small intestine injury by NSAIDs is complex and different from that of the upper gastrointestinal tract. No drug has yet been developed that can completely prevent or treat NSAID enteropathy. Therefore, a long-term randomized study in chronic NSAID users is needed. (C) 2011 Baishideng. All rights reserved.
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