Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 15, Issue 10, Pages 1168-1177Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.15.1168
Keywords
Models; Acute alcohol abuse; Human; Non-human; Progress
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Funding
- NIAAAA [AA016571, AA014372]
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Alcohol abuse is a global problem due to the financial burden on society and the healthcare system. While the harmful health effects of chronic alcohol abuse are well established, more recent data suggest that acute alcohol consumption also affects human wellbeing. Thus, there is a need for research models in order to fully understand the effect of acute alcohol abuse on different body systems and organs. The present manuscript summarizes the interdisciplinary advantages and disadvantages of currently available human and non-human models of acute alcohol abuse, and identifies their suitability for biomedical research. (c) 2009 The WJG Press and Baishideng. All rights reserved.
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