Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 15, Issue 17, Pages 2170-2171Publisher
BAISHIDENG PUBL GRP CO LTD
DOI: 10.3748/wjg.15.2170
Keywords
Nigella sativa; Thymoquinone; Colon cancer; Glutathione-S transferase; Schistosomiasis
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Nigella sativa decreases DNA damage and thereby prevents initiation of carcinogenesis in colonic tissue secondary to exposure to toxic agents such as azoxymethane. N. sativa is of immense therapeutic benefit in diabetic individuals and those with glucose intolerance as it accentuates glucose-induced secretion of insulin besides having a negative impact on glucose absorption from the intestinal mucosa. N. sativa administration protects hepatic tissue from deleterious effects of toxic metals such as lead, and attenuates hepatic lipid peroxidation following exposure to chemicals such as carbon tetrachloride. (C) 2009 The WIG Press and Baishideng. All rights reserved
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