Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 14, Issue 29, Pages 4593-4599Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.14.4593
Keywords
end stage liver disease; liver failure treatment; stem cells; regenerative medicine
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End stage liver disease (ESLD) is a health problem worldwide. Liver transplantation is currently the only effective therapy, but its many drawbacks include a shortage of donors, operative damage, risk of rejection and in some cases recidivism of the pre-transplant disease. These factors account for the recent growing interest in regenerative medicine. Experiments have sought to identify an optimal source of stem cells, sufficient to generate large amounts of hepatocytes to be used in bioartificial livers or injected in vivo to repair the diseased organ. This update aims to give non-stem cell specialists an overview of the results obtained to date in this fascinating field of biomedical research. (c) 2008 The WJG Press. All rights reserved.
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