Journal
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 14, Issue 39, Pages 6083-6086Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.14.6083
Keywords
Collagenous colitis; Protein-losing enteropathy; Prednisolone; 99mTc-human serum albumin scintigraphy; chronic diarrhea
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A 76-year-old woman with a 5-mo history of recurrent diarrhea and generalized edema was admitted to our hospital. Colonoscopy revealed edematous mucosa, and histopathological examination was compatible with collagenous colitis. Protein leakage from the colon, particularly in the ascending portion, was identified on 99mTc-human serum albumin scintigraphy. Collagenous colitis associated with protein-losing enteropathy (PLE) without small bowel disease was diagnosed. Prednisolone treatment ameliorated diarrhea and hypoproteinemia. Collagenous colitis should be included in the differential diagnosis of chronic diarrhea with hypoproteinemia for appropriate management. (c) 2008 The WJG Press. All rights reserved.
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