Journal
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
Volume 1, Issue 4, Pages 353-359Publisher
WILEY
DOI: 10.1002/wnan.27
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Nanoparticles arise from a wide variety of natural and man-made sources and have a diverse array of biological, chemical, and physical properties. The toxicity of these particles can be roughly divided into two categories: 1) the enhanced delivery of toxic agents 2) toxicity induced the properties of the particle itself. The use of nanoparticles to provide enhanced delivery of chemotherapeutics is presented followed by a discussion of the size-based effects of electron transfer and physical membrane disruption. (C) 2009 John Wiley & Sons, Inc. WIREs Nanomed Nanobiotechnol 2009 1 353-359
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