4.4 Article

ALLMAPS: robust scaffold ordering based on multiple maps

Journal

GENOME BIOLOGY
Volume 16, Issue -, Pages -

Publisher

BMC
DOI: 10.1186/s13059-014-0573-1

Keywords

-

Funding

  1. Fujian provincial government
  2. Gordon and Betty Moore Foundation [3383]
  3. National Science Foundation [DBI-0735191, DBI-1265383]

Ask authors/readers for more resources

The ordering and orientation of genomic scaffolds to reconstruct chromosomes is an essential step during de novo genome assembly. Because this process utilizes various mapping techniques that each provides an independent line of evidence, a combination of multiple maps can improve the accuracy of the resulting chromosomal assemblies. We present ALLMAPS, a method capable of computing a scaffold ordering that maximizes colinearity across a collection of maps. ALLMAPS is robust against common mapping errors, and generates sequences that are maximally concordant with the input maps. ALLMAPS is a useful tool in building high-quality genome assemblies. ALLMAPS is available at: https://github.com/tanghaibao/jcvi/wiki/ALLMAPS.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available