Journal
GENOME BIOLOGY
Volume 16, Issue -, Pages -Publisher
BIOMED CENTRAL LTD
DOI: 10.1186/s13059-015-0621-5
Keywords
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Funding
- Wellcome Trust [WT095908]
- National Human Genome Research Institute [1U01 HG004695, 5U01HG004695]
- Biotechnology and Biological Sciences Research Council [BB/I025360/2]
- European Molecular Biology Laboratory
- European Union [282510, 223210]
- European Commission [018883, 226073]
- Wellcome Trust [WT095908]
- National Human Genome Research Institute [1U01 HG004695, 5U01HG004695]
- Biotechnology and Biological Sciences Research Council [BB/I025360/2]
- European Molecular Biology Laboratory
- European Union [282510, 223210]
- European Commission [018883, 226073]
- BBSRC [BB/I025360/2] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/I025360/2] Funding Source: researchfish
Ask authors/readers for more resources
Most genomic variants associated with phenotypic traits or disease do not fall within gene coding regions, but in regulatory regions, rendering their interpretation difficult. We collected public data on epigenetic marks and transcription factor binding in human cell types and used it to construct an intuitive summary of regulatory regions in the human genome. We verified it against independent assays for sensitivity. The Ensembl Regulatory Build will be progressively enriched when more data is made available. It is freely available on the Ensembl browser, from the Ensembl Regulation MySQL database server and in a dedicated track hub.
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