Journal
WATER RESEARCH
Volume 46, Issue 4, Pages 955-964Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.watres.2011.11.063
Keywords
Trametes versicolor; Pharmaceuticals; Carbamazepine; Bioreactor; Continuous treatment
Funding
- Spanish Ministry of Science and Innovation [CTM2007/60971/TECNO, CSD2009-00065]
- CSIC (Consejo Superior de Investigaciones Cientificas)
- European Social Funds, for a predoctoral grant
- UAB
- ICREA Funding Source: Custom
Ask authors/readers for more resources
The paper describes the aerobic degradation of carbamazepine (CBZ), an anti-epileptic drug widely found in aquatic environment, from Erlenmeyer flask to bioreactor by the white-rot fungus Trametes versicolor. In Erlenmeyer flask, CBZ at approximately 9 mg L-1 was almost completely eliminated (94%) after 6 d, while at near environmentally relevant concentrations of 50 mu g L-1, 61% of the contaminant was degraded in 7 d. Acridone, acridine, 10,11-dihydro-10,11-dihydroxy-CBZ, and 10, 11-epoxy-CBZ were identified as major metabolites, confirming the degradation of CBZ. The degradation process was then carried out in an air pulsed fluidized bioreactor operated in batch and continuous mode. Around 96% of CBZ was removed after 2 days in batch mode operation, and 10,11-dihydro-10,11-epoxycarbamazepine was found as unique metabolite. In bioreactor operated in continuous mode with a hydraulic retention time of 3 d, 54% of the inflow concentration (approx. 200 mu g L-1) was reduced at the steady state (25 d) with a CBZ degradation rate of 11.9 mu g CBZ g(-1) dry weight d(-1). No metabolite was detected in the culture broth. Acute toxicity tests (Microtox) indicated that the final culture broth in both batch and continuous mode operation were non toxic, with 15 min EC50 values of 24% and 77%, respectively. (C) 2011 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available