Journal
WASTE MANAGEMENT & RESEARCH
Volume 30, Issue 3, Pages 217-224Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0734242X11404733
Keywords
Biomaterials; immunological responses; protein cross-linking; silk sericin
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Funding
- National Research Council of Thailand
- Thailand Research Fund
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Silk is composed of two major proteins, fibroin (fibrous protein) and sericin (globular, gumming protein). Fibroin has been used in textile manufacturing and for several biomaterial applications, whereas sericin is considered a waste material in the textile industry. Sericin has recently been found to activate the proliferation of several cell-lines and has also shown various biological activities. Sericin can form a gel by itself; however, after mixing with other polymers and cross-linking it can form a film or a scaffold with good characteristics that can be used in the cosmetic and pharmaceutical industries. Sericin is proven to cause no immunological responses, which has resulted in a more acceptable material for biological applications.
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