Journal
VIRUS RESEARCH
Volume 171, Issue 1, Pages 1-7Publisher
ELSEVIER
DOI: 10.1016/j.virusres.2012.11.002
Keywords
Neutrophil; Viral pathogenesis
Categories
Funding
- National Center for Research Resources [5P20RR016476-11]
- National Institute of General Medical Sciences from the National Institutes of Health [8 P20 GM103476-11]
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Polymorphonuclear leukocytes or neutrophils are the first immune cells to the site of injury and microbial infection. Neutrophils are crucial players in controlling bacterial and fungal infections, and in particular secondary infections, by phagocytosis, degranulation and neutrophil extracellular traps (NETs). While neutrophils have been shown to play important roles in viral pathogenesis, there is a lack of detailed investigation. In this article, we will review recent progresses toward understanding the role of neutrophils in viral pathogenesis. (C) 2012 Elsevier B.V. All rights reserved.
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