Journal
VIRUS RESEARCH
Volume 149, Issue 2, Pages 197-210Publisher
ELSEVIER
DOI: 10.1016/j.virusres.2010.01.018
Keywords
Rabies; Lyssavirus; Rhabdovirus; Shimoni bat virus; Phylogeny; Chiroptera; Zoonosis; Africa; Kenya
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Funding
- Centers for Disease Control and Prevention (Atlanta, GA)
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During 2009, 616 bats representing at least 22 species were collected from 10 locations throughout Kenya. A new lyssavirus, named Shimoni bat virus (SHIBV), was isolated from the brain of a dead Commerson's leaf-nosed bat (Hipposideros commersoni), found in a cave in the coastal region of Kenya. Genetic distances and phylogenetic reconstructions, implemented for each gene and for the concatenated alignment of all five structural genes (N, P, M, G and L), demonstrated that SHIBV cannot be identified with any of the existing species, but rather should be considered an independent species within phylogroup II of the Lyssavirus genus, most similar to Lagos bat virus (LBV). Antigenic reaction patterns with anti-nucleocapsid monoclonal antibodies corroborated these distinctions. In addition, new data on the diversity of LBV suggests that this species may be subdivided quantitatively into three separate genotypes. However, the identity values alone are not considered sufficient criteria for demarcation of new species within LBV. Published by Elsevier B.V.
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