Journal
VIRUS RESEARCH
Volume 147, Issue 1, Pages 17-24Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.virusres.2009.09.013
Keywords
Moussa rhabdovirus; Culex decens mosquitoes; Phylogeny; High-throughput pyrosequencing; Ivory Coast/Cote d'Ivoire; Africa
Categories
Funding
- Robert Koch-Institute
- Max-Planck-Society
- Google.org
- National Institutes of Health [AI051292, AI57158]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [U54AI057158, R01AI051292] Funding Source: NIH RePORTER
Ask authors/readers for more resources
Characterization of arboviruses at the interface of pristine habitats and anthropogenic landscapes is crucial to comprehensive emergent disease surveillance and forecasting efforts. In context of a surveillance campaign in and around a West African rainforest, particles morphologically consistent with rhabdoviruses were identified in cell cultures infected with homogenates of trapped mosquitoes. RNA recovered from these cultures was used to derive the first complete genome sequence of a rhabdovirus isolated from Culex decens mosquitoes in Cote d'Ivoire, tentatively named Moussa virus (MOUV). MOUV shows the classical genome organization of rhabdoviruses, with five open reading frames (ORF) in a linear order. However, sequences show only limited conservation (12-33% identity at amino acid level), and ORF2 and ORF3 have no significant similarity to sequences deposited in GenBank. Phylogenetic analysis indicates a potential new species with distant relationship to Tupaia and Tibrogargan virus. (c) 2009 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available