Journal
VIROLOGY
Volume 454, Issue -, Pages 340-352Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.virol.2014.02.021
Keywords
HIV cure; Eradication; Remission of HIV infection; HIV reservoirs; Reactivation of latent virus; Repression of provirus; Control of infection
Categories
Funding
- ANRS
- Sidaction
- amfAR
- Total Foundation
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Thirty years after the identification of HIV, a cure for HIV infection is still to be achieved. Advances of combined antiretroviral therapy (cART) in recent years have transformed HIV infection into a chronic disease when treatment is available. However, in spite of the favorable outcomes provided by the newer therapies, CART is not curative and patients are at risk of developing HIV-associated disorders. Moreover, universal access to antiretroviral treatment is restricted by financial obstacles. This review discusses the most recent strategies that have been developed in the search for an HIV cure and to improve life quality of people living with HIV. (c) 2014 Elsevier Inc. All rights reserved.
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