Journal
EXPERT REVIEW OF NEUROTHERAPEUTICS
Volume 15, Issue 5, Pages 509-522Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/14737175.2015.1034108
Keywords
behavior; C9orf72; clinical continuum; cognition; Frontotemporal dementia; genetics; motor neuron disease; neuroimaging; neurophysiology
Categories
Funding
- National Health and Medical research Council of Australia [1037746]
- Australian Research Council Centre of Excellence in Cognition and its Disorders Memory Node [CE110001021]
- University of New South Wales
- MND Association UK
Ask authors/readers for more resources
Overlap between motor neuron disease (MND) and frontotemporal dementia (FTD) occurs at clinical, genetic and pathological levels, and has been recently strengthened through the discovery of the C9orf72 genetic expansion. MND is now considered to be a multisystem disorder in which cognitive involvement may be present and, in some cases, may evolve to frank FTD. Identifying cognitive features in MND can be challenging, while, similarly, motor dysfunction in FTD may be overlooked. As such, the present review aims to decipher the variety of overlapping clinical features across the MND-FTD continuum.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available