Related references
Note: Only part of the references are listed.DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
Anetta Hartlova et al.
IMMUNITY (2015)
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
Jing Liao et al.
NATURE GENETICS (2015)
SAMHD1 prevents autoimmunity by maintaining genome stability
Stefanie Kretschmer et al.
ANNALS OF THE RHEUMATIC DISEASES (2015)
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity
Claudia Guenther et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Notes on the role of dynamic DNA methylation in mammalian development
Timothy H. Bestor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
StochHMM: a flexible hidden Markov model tool and C plus plus library
Paul C. Lott et al.
BIOINFORMATICS (2014)
SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage
Ruth Clifford et al.
BLOOD (2014)
Cytosolic RNA:DNA hybrids activate the cGAS-STING axis
Arun K. Mankan et al.
EMBO JOURNAL (2014)
RNA:DNA hybrids are a novel molecular pattern sensed by TLR9
Rachel E. Rigby et al.
EMBO JOURNAL (2014)
Strand-Specific Analysis Shows Protein Binding at Replication Forks and PCNA Unloading from Lagging Strands when Forks Stall
Chuanhe Yu et al.
MOLECULAR CELL (2014)
Transcript-RNA-templated DNA recombination and repair
Havva Keskin et al.
NATURE (2014)
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
Gillian I. Rice et al.
NATURE GENETICS (2014)
The enemy within: endogenous retroelements and autoimmune disease
Hannah E. Volkman et al.
NATURE IMMUNOLOGY (2014)
Transcription-Associated R-Loop Formation across the Human FMR1 CGG-Repeat Region
Erick W. Loomis et al.
PLOS GENETICS (2014)
Common and specific signatures of gene expression and protein-protein interactions in autoimmune diseases
T. Tuller et al.
GENES AND IMMUNITY (2013)
Dynamic DNA methylation across diverse human cell lines and tissues
Katherine E. Varley et al.
GENOME RESEARCH (2013)
GC skew at the 5′ and 3′ ends of human genes links R-loop formation to epigenetic regulation and transcription termination
Paul A. Ginno et al.
GENOME RESEARCH (2013)
A critical role for interleukin-1β in the progression of autoimmune diseases
Ruijuan Zhao et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2013)
Impaired DNA methylation and its mechanisms in CD4+T cells of systemic lupus erythematosus
Yiqun Zhang et al.
JOURNAL OF AUTOIMMUNITY (2013)
Assessment of interferon-related biomarkers in Aicardi-Goutieres syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study
Gillian I. Rice et al.
LANCET NEUROLOGY (2013)
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
Manuel Luis Orta et al.
NUCLEIC ACIDS RESEARCH (2013)
DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking
Takeshi Kondo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The human placenta methylome
Diane I. Schroeder et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun et al.
SCIENCE (2013)
Modulation of LINE-1 and Alu/SVA Retrotransposition by Aicardi-Goutieres Syndrome-Related SAMHD1
Ke Zhao et al.
CELL REPORTS (2013)
Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+T-cell Populations
Devin M. Absher et al.
PLOS GENETICS (2013)
Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
Martin A. M. Reijns et al.
CELL (2012)
Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity
Bjoern Hiller et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters
Paul A. Ginno et al.
MOLECULAR CELL (2012)
R Loops: From Transcription Byproducts to Threats to Genome Stability
Andres Aguilera et al.
MOLECULAR CELL (2012)
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains
Benjamin P. Berman et al.
NATURE GENETICS (2012)
Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature
Gillian I. Rice et al.
NATURE GENETICS (2012)
Autosomal Dominant Inheritance of a Heterozygous Mutation in SAMHD1 Causing Familial Chilblain Lupus
Jane C. Ravenscroft et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2011)
Type I interferonopathies: a novel set of inborn errors of immunity
Yanick J. Crow
YEAR IN HUMAN AND MEDICAL GENETICS: INBORN ERRORS OF IMMUNITY I (2011)
Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications
Felix Krueger et al.
BIOINFORMATICS (2011)
Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
Matlock A. Jeffries et al.
EPIGENETICS (2011)
Large-scale methylation domains mark a functional subset of neuronally expressed genes
Diane I. Schroeder et al.
GENOME RESEARCH (2011)
Cutting Edge: Ku70 Is a Novel Cytosolic DNA Sensor That Induces Type III Rather Than Type I IFN
Xing Zhang et al.
JOURNAL OF IMMUNOLOGY (2011)
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
David C. Goldstone et al.
NATURE (2011)
PCNA directs type 2 RNase H activity on DNA replication and repair substrates
Doryen Bubeck et al.
NUCLEIC ACIDS RESEARCH (2011)
BEDTools: a flexible suite of utilities for comparing genomic features
Aaron R. Quinlan et al.
BIOINFORMATICS (2010)
Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells
R. David Hawkins et al.
CELL STEM CELL (2010)
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
Biola M. Javierre et al.
GENOME RESEARCH (2010)
Identification of a Functional Network of Human Epigenetic Silencing Factors
Andrey Poleshko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Epigenetic Instability due to Defective Replication of Structured DNA
Peter Sarkies et al.
MOLECULAR CELL (2010)
Genome instability due to ribonucleotide incorporation into DNA
Stephanie A. Nick McElhinny et al.
NATURE CHEMICAL BIOLOGY (2010)
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
Julie A. Law et al.
NATURE REVIEWS GENETICS (2010)
Differential expression analysis for sequence count data
Simon Anders et al.
GENOME BIOLOGY (2010)
TopHat: discovering splice junctions with RNA-Seq
Cole Trapnell et al.
BIOINFORMATICS (2009)
Fast and accurate short read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2009)
Ribonuclease H: the enzymes in eukaryotes
Susana M. Cerritelli et al.
FEBS JOURNAL (2009)
Circos: An information aesthetic for comparative genomics
Martin Krzywinski et al.
GENOME RESEARCH (2009)
Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity
Yanick J. Crow et al.
HUMAN MOLECULAR GENETICS (2009)
Human DNA methylomes at base resolution show widespread epigenomic differences
Ryan Lister et al.
NATURE (2009)
Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response
Gillian I. Rice et al.
NATURE GENETICS (2009)
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
Da Wei Huang et al.
NATURE PROTOCOLS (2009)
Trex1 prevents cell-intrinsic initiation of autoimmunity
Daniel B. Stetson et al.
CELL (2008)
Model-based Analysis of ChIP-Seq (MACS)
Yong Zhang et al.
GENOME BIOLOGY (2008)
DNA methylation inhibitor 5-aza-2 '-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B
Stela S. Palii et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease
Yun-Gui Yang et al.
CELL (2007)
Clinical and molecular phenotype of Aicardi-Goutieres syndrome
Gillian Rice et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus
Min Ae Lee-Kirsch et al.
NATURE GENETICS (2007)
Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome
Gillian Rice et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2007)
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
Taiping Chen et al.
NATURE GENETICS (2007)
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
Lothar Schermelleh et al.
NUCLEIC ACIDS RESEARCH (2007)
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection
Yanick J. Crow et al.
NATURE GENETICS (2006)
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
Yanick J. Crow et al.
NATURE GENETICS (2006)
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
Akiko Tsumura et al.
GENES TO CELLS (2006)
The epigenetic face of systemic lupus erythematosus
E Ballestar et al.
JOURNAL OF IMMUNOLOGY (2006)
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
EC Baechler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
L Jackson-Grusby et al.
NATURE GENETICS (2001)
A Toll-like receptor recognizes bacterial DNA
H Hemmi et al.
NATURE (2000)
Share Paper
