Journal
VETERINARY PATHOLOGY
Volume 47, Issue 1, Pages 163-166Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/0300985809354347
Keywords
Bartonella adhesin A; Bartonella henselae; feline; immunohistochemistry; liver; nested polymerase chain reaction; peliosis hepatis
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Funding
- H. Wilhelm Schaumann Foundation, Germany
- DFG
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Peliosis hepatis is a vasculoproliferative disorder of the liver with infectious and noninfectious causes. In humans and dogs, Bartonella henselae has been linked to peliosis hepatis. Although domestic cats are the natural reservoir of B. henselae and although peliosis hepatis is common in this species, an association between this condition and infection with B. henselae has never been investigated in cats. In this study, 26 cases of peliosis hepatis in cats were tested for B. henselae infection by nested polymerase chain reaction and immunohistochemistry. The authors failed to detect B. henselae nucleic acid or antigen in any of the affected liver specimens. These findings suggest that, unlike in humans and dogs, peliosis hepatis in cats may not be significantly associated with a B. henselae infection.
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