Journal
VETERINARY JOURNAL
Volume 180, Issue 1, Pages 130-132Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tvjl.2007.11.010
Keywords
Foot-and-mouth disease; Foot-and-mouth disease virus; FMD; Real-time RT-PCR; Persistence
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Funding
- Department for Environment, Food and Rural Affairs (DEFRA), UK
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Quantitative analysis of the duration of foot-and-mouth disease virus (FMDV) RNA in tissues was carried out in pigs experimentally infected with FMDV O UKG 34/2001 and O SKR 1/2000. The results showed that the viral RNA was still detectable in cervical lymph nodes, mandibular lymph nodes and tonsils collected froth both inoculated and contact pigs at 28 days post infection. There was no detectable viral RNA in the soft palate or pharynx, which are thought to be tissue sites for viral persistence in cattle. Further study is needed to clarify whether this difference has significance in terms of viral clearance in pigs. (c) 2007 Elsevier Ltd. All rights reserved.
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