4.2 Article

Melamine and Cyanuric Acid-induced Crystalluria, Uroliths, and Nephrotoxicity in Dogs and Cats

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cvsm.2008.09.010

Keywords

Melamine; Cyanuric acid; Uric acid monohydrate; Nephrotoxicity; Wheat gluten; Uroliths; Crystalluria

Funding

  1. National Science Foundation through the National Nanotechnology Infrastructure Network program

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This article discusses the 2007 recall of canned pet food because of concerns about adverse effects on kidney function of cats and dogs. The discovery of melamine and cyanuric acid in the foods is detailed. Case studies, including clinical, pathology, histology, and toxicology findings, are presented. An attempt is being made to identify the minerals in the uroliths and kidney tissues of affected animals.

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