Journal
VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE
Volume 30, Issue 3, Pages 579-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cveq.2014.08.004
Keywords
Hendra; Horse; Pathogenesis; Vaccine; Emerging; Zoonotic; Infectious; Disease
Categories
Funding
- National Health and Medical Research Council [1022516]
- National Institutes of Health [U01-A107795]
- Commonwealth of Australia
- Queensland State Government, Intergovernmental Hendra Virus Taskforce
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Hendra virus infection of horses occurred sporadically between 1994 and 2010 as a result of spill-over from the viral reservoir in Australian mainland flying-foxes, and occasional onward transmission to people also followed from exposure to affected horses. An unprecedented number of outbreaks were recorded in 2011 leading to heightened community concern. Release of an inactivated subunit vaccine for horses against Hendra virus represents the first commercially available product that is focused on mitigating the impact of a Biosafety Level 4 pathogen. Through preventing the development of acute Hendra virus disease in horses, vaccine use is also expected to reduce the risk of transmission of infection to people.
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