Journal
BMJ-BRITISH MEDICAL JOURNAL
Volume 350, Issue -, Pages -Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/bmj.h2147
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Funding
- Chief Scientist Office (CSO) of Scotland [CZH/4/773]
- UK Medical Research Council
- University of Dundee
- Health Services Research Unit at the University of Aberdeen - CSO of the Scottish Government Health Directories
- Chief Scientist Office [CZH/4/773, NMAHP2, HSRU1] Funding Source: researchfish
- Medical Research Council [1415468] Funding Source: researchfish
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PRECIS is a tool to help trialists make design decisions consistent with the intended purpose of their trial. This paper gives guidance on how to use an improved, validated version, PRECIS-2, which has been developed with the help of over 80 international trialists, clinicians, and policymakers. Keeping the original simple wheel format, PRECIS-2 has nine domains-eligibility criteria, recruitment, setting, organisation, flexibility (delivery), flexibility (adherence), follow-up, primary outcome, and primary analysis-scored from 1 (very explanatory) to 5 (very pragmatic) to facilitate domain discussion and consensus. It is hoped PRECIS-2 will be valuable in supporting the explicit matching of design decisions to how the trial results are intended to be used
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