Journal
VACCINE
Volume 28, Issue 15, Pages 2700-2704Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2010.01.021
Keywords
Influenza surveillance; Influenza vaccination; HIV infection
Categories
Funding
- Istituto Superiore di Sanita [30G.31]
- VI Programma Nazionale di Ricerca sull'AIDS
- Ministero dell'Universita e delta Ricerca [2007LPAF42_003]
- Progetti di Ricerca di Interesse Nazionale (PRIN)
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During the 2006-2007 season, 19 HIV-uninfected and 33 HIV-infected children and adolescents with full immunovirologic response to HAART were immunized against influenza and subsequently followed up. One month post-immunization all subjects had protective antibodies titres which persisted for the whole influenza season. Seven vaccinees (four HIV-infected and three HIV-uninfected) were found to be infected by influenza viruses during the epidemic, but disease was lab-confirmed only in two HIV-infected subjects. Both presented a benign clinical course and were infected by an A/Brisbane/10/07-H3N2-like virus. These data indicate that HIV-infected subjects benefit from routine seasonal influenza vaccination. (C) 2010 Elsevier Ltd. All rights reserved.
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