4.5 Article

HIV-1 assembly at the plasma membrane

Journal

VACCINE
Volume 28, Issue -, Pages B55-B59

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2009.10.021

Keywords

Gag; Assembly; P1(4,5)P(2); Plasma membrane; Matrix

Funding

  1. NIAID NIH HHS [R01 AI071727-03, R01 AI071727, R01 AI071727-02, R01 AI071727-01A1] Funding Source: Medline

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HIV-1 particle assembly takes place at the plasma membrane, which likely enhances release of extracellular vinous and spread to next target cells. Recent work by our lab and others started to reveal a molecular mechanism by which HIV ensures to make the plasma membrane as a primary site of virus assembly. (C) 2009 Elsevier Ltd. All rights reserved.

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