Journal
VACCINE
Volume 28, Issue 23, Pages 3875-3882Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2010.03.074
Keywords
Vaccine; Influenza; Memory; Antigen production
Categories
Funding
- MRC [G0700846] Funding Source: UKRI
- Medical Research Council [G0700846] Funding Source: researchfish
- Medical Research Council [G0700846] Funding Source: Medline
Ask authors/readers for more resources
Current influenza vaccines are limited by the need for annual immunisation, frequent antigenic updating to match the evolution of circulating influenza virus strains, and reduced efficacy in elderly persons. On 9-10 November 2009, the Initiative for Vaccine Research of the World Health Organization convened jointly with the Wellcome Trust in London, United Kingdom, the fourth meeting on 'Influenza vaccines that induce broad spectrum and long-lasting immune responses'. Presentations were made by representatives from industry, academia, governmental and non-governmental organisations. The objectives of the meeting were to update the progress of research in the field of influenza vaccine strategies able to generate cross protection against divergent influenza virus strains. Improvements in existing strategies including live attenuated influenza vaccines and adjuvantation of inactivated vaccines were summarised. Developments in novel antigen production methods, new routes of vaccine delivery and administration, and vaccine approaches based on conserved virus antigens were explored. In addition, correlates of immune protection and regulatory issues for the evaluation and approval of future novel vaccine strategies were discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available