Journal
VACCINE
Volume 27, Issue 13, Pages 1923-1927Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.vaccine.2009.01.108
Keywords
Influenza; Older adults; Herd immunity
Categories
Funding
- MedImmune
- VTEU [N01 AI25462]
- NIH/NCRR [5 K12 RR017697-05,]
- NIAID [IK23AI074863-01, K23AI065805]
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The extent to which immunizing school children reduce the burden of influenza in adults is controversial. We enrolled a systematic sample of adults >= 50 years hospitalized with respiratory symptoms in two counties, one with and one without a school-based immunization program. We tested all Subjects for influenza by polymerase chain reaction. Hospitalizations per 1000 adults aged >= 50 years were 1.28 (95% Cl 0.59, 2.04) in the intervention county and 1.53 (95% Cl 0.71, 2.34) in the Control County. These rates did not differ significantly except in the subgroup aged 50-64 years where rates in the intervention county were significantly lower. (C) 2009 Elsevier Ltd. All rights reserved.
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