Journal
BIOMED RESEARCH INTERNATIONAL
Volume 2015, Issue -, Pages -Publisher
HINDAWI LTD
DOI: 10.1155/2015/385428
Keywords
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Funding
- World Class Laboratory (WCL) Grant from Korea Research Institute of Standards and Science
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We investigated T-1 relaxations of ex-vivo cancer tissues at low magnetic fields in order to check the possibility of achieving a T-1 contrast higher than those obtained at high fields. The T-1 relaxations of fifteen pairs (normal and cancerous) of breast tissue samples were measured at three magnetic fields, 37, 62, and 122 mu T, using our superconducting quantum interference device-based ultralow field nuclear magnetic resonance setup, optimally developed for ex-vivo tissue studies. A signal reconstruction based on Bayesian statistics for noise reduction was exploited to overcome the low signal-to-noise ratio. The ductal and lobular-type tissues did not exhibit meaningful T-1 contrast values between normal and cancerous tissues at the three different fields. On the other hand, an enhanced T-1 contrast was obtained for the mucinous cancer tissue.
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