4.5 Article

THE SPEED OF SOUND AND ATTENUATION OF AN IEC AGAR-BASED TISSUE-MIMICKING MATERIAL FOR HIGH FREQUENCY ULTRASOUND APPLICATIONS

Journal

ULTRASOUND IN MEDICINE AND BIOLOGY
Volume 38, Issue 7, Pages 1262-1270

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.ultrasmedbio.2012.02.030

Keywords

Ultrasound; High frequency; Tissue mimicking material; Speed of sound; Attenuation; Frequency dependence

Funding

  1. China Scholarship Council/University of Edinburgh
  2. Wellcome Trust [WT083227AIA]
  3. MRC [G0800896] Funding Source: UKRI
  4. Medical Research Council [G0800896] Funding Source: researchfish

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This study characterized the acoustic properties of an International Electromechanical Commission (IEC) agar-based tissue mimicking material (TMM) at ultrasound frequencies in the range 10-47 MHz. A broad-band reflection substitution technique was employed using two independent systems at 21 degrees C +/- 1 degrees C. Using a commercially available preclinical ultrasound scanner and a scanning acoustic macroscope, the measured speeds of sound were 1547.4 +/- 1.4 m.s(-1) and 1548.0 +/- 6.1 m.s(-1), respectively, and were approximately constant over the frequency range. The measured attenuation (dB.cm(-1)) was found to vary with frequency f (MHz) as 0.40f + 0.0076f(2). Using this polynomial equation and extrapolating to lower frequencies give values comparable to those published at lower frequencies and can estimate the attenuation of this TMM in the frequency range up to 47 MHz. This characterisation enhances understanding in the use of this TMM as a tissue equivalent material for high frequency ultrasound applications. (E-mail: C.Sun-2@sms.ed.ac.uk) (C) 2012 World Federation for Ultrasound in Medicine & Biology.

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