4.5 Article

SKELETAL MUSCLE ULTRASOUND: CORRELATION BETWEEN FIBROUS TISSUE AND ECHO INTENSITY

Journal

ULTRASOUND IN MEDICINE AND BIOLOGY
Volume 35, Issue 3, Pages 443-446

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.ultrasmedbio.2008.09.016

Keywords

Ultrasound; Echo intensity; Neuromuscular disorders; Duchenne muscular dystrophy; Dogs; Muscle

Funding

  1. Prinses Beatrix Fonds [MAR02-0105]
  2. Netherlands Organization for Health Research and Development [907 to 00-057]

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In this study, we examined the correlation between muscle ultrasound and muscle structure. Echo intensity (EI) or 14 muscles of two golden retriever muscular dystrophy dogs was correlated to the percentage interstitial fibrous tissue and fat in muscle biopsy. A significant correlation between interstitial fibrous tissue and EI was found (r = 0.87;p < 0.001). The separate influence of interstitial fat on muscle EI could not be established as only little fat was present, We conclude that fibrous tissue causes increased muscle EI. The high correlation between interstitial fibrous tissue and EI makes ultrasound a reliable method to determine severity of structural muscle changes. (E-mail: s.pillen@cukz.umcn.nl) (C) 2009 World Federation for Ultrasound in Medicine & Biology.

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