Journal
ULTRASONICS SONOCHEMISTRY
Volume 19, Issue 2, Pages 264-269Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ultsonch.2011.07.006
Keywords
Dispiroheterocyclic compound; 1,3-Dipolar cycloaddition; Azomethine ylide; Ultrasound
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Funding
- Foundation of the Natural Science Foundation of China [21072144]
- Natural Science Foundation of the Jiangsu Higher Education Institutions [10KJA150049]
- Jiangsu Higher Education Institutions
- Key Laboratory of Organic Synthesis of Jiangsu Province [KJS0812]
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A facile and efficient one-pot three-component procedure for synthesis of novel dispirooxindolecyclo[pyrrolo[1,2-c]thiazole-6,5'-thiazolidine] derivatives without any catalysts under ultrasonic condition has been developed. Combining with the advantages of sonochemistry, such as mild reaction conditions, good yield and short reaction times, we have made a progress on construction of novel disiproheterocyclic compounds via the 1,3-dipolar cycloaddition of azomethine ylides. Several experiments were especially carried out for investigating the acceleration mechanism of ultrasound on the cycloaddition. (C) 2011 Elsevier B.V. All rights reserved.
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