4.7 Article

Ultrasound-radiated synthesis of PAMAM-Au nanocomposites and its application on glucose biosensor

Journal

ULTRASONICS SONOCHEMISTRY
Volume 17, Issue 1, Pages 17-20

Publisher

ELSEVIER
DOI: 10.1016/j.ultsonch.2009.06.017

Keywords

PAMAM-Au; Ultrasound irradiation; Glucose oxidase; Glucose biosensor

Funding

  1. Science and Technology Commission of Shanghai Municipality [06dz05824]
  2. National Natural Science Foundation of China [20475017]

Ask authors/readers for more resources

Hybrid nanocomposites of carboxyl-terminated generation 4 (G 4) poly(amidoamine) dendrimers (PAMAM) with gold nanoparticles (AuNPs) encapsulated inside them were synthesized under ultrasound irradiation, The obtained nanocomposites were used to fabricate highly sensitive amperometric glucose biosensor which exhibited a high and reproducible sensitivity of 2.9 mA/mM/cm(2), response time less than 5 s, linear dynamic range from 0.1 to 15.8 mu M, correlation coefficient of R-2 = 0.9988, and limit of detection (LOD), based on S/N ratio (S/N = 3) of 0.05 mu M. A value of 2.7 mM for the apparent Michaelis-Menten constant K-M(app) was obtained. The high sensitivity, wider linear range, good reproducibility and stability make this biosensor a promising candidate for portable amperometric glucose biosensor. (C) 2009 Elsevier B.V. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available