Journal
ULTRAMICROSCOPY
Volume 111, Issue 4, Pages 282-284Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ultramic.2010.12.018
Keywords
Coherent diffraction; Low-energy electrons; Microlens; Single molecule imaging
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Funding
- Swiss National Science Foundation
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Today's structural biology techniques require averaging over millions of molecules to obtain detailed structural information. Derivation of the molecular structure from a scattering experiment with just one single 3D-molecule imposes major challenges. Coherent and damage-free radiation is needed to ensure sufficient elastic scattering events before destroying the molecule and a means to solve the phase problem is wanted. We have devised such a scheme using coherent low-energy electrons shaped into a collimated beam by an electrostatic microlens. Initial experiments using a carbon nanotube sample demonstrate the feasibility of coherent low-energy electron diffraction on an individual nanometer-sized object. (C) 2010 Elsevier B.V. All rights reserved.
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